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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLK2
All Species:
30.91
Human Site:
Y413
Identified Species:
61.82
UniProt:
P49760
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49760
NP_003984.2
499
60090
Y413
R
K
T
R
K
Q
K
Y
F
Y
R
G
R
L
D
Chimpanzee
Pan troglodytes
XP_513855
498
59985
Y412
R
K
T
R
K
Q
K
Y
F
Y
R
G
R
L
D
Rhesus Macaque
Macaca mulatta
XP_001100690
638
73454
Y554
H
R
T
R
K
Q
K
Y
F
Y
K
G
G
L
V
Dog
Lupus familis
XP_547549
536
63798
Y449
R
K
T
R
K
Q
K
Y
F
Y
R
G
R
L
D
Cat
Felis silvestris
Mouse
Mus musculus
O35491
499
59936
Y412
R
K
T
R
K
Q
K
Y
F
Y
R
G
R
L
D
Rat
Rattus norvegicus
Q63117
490
58467
Y406
H
R
T
R
K
Q
K
Y
F
Y
K
G
G
L
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZIU3
526
59419
T394
P
R
Y
C
T
I
T
T
L
S
D
G
S
I
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038344
526
62655
Y437
R
K
T
R
K
Q
K
Y
F
Y
R
G
R
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49762
832
95705
Y733
Y
S
K
T
K
T
K
Y
F
Y
H
G
K
L
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XTF3
817
89866
S708
P
R
Y
C
T
A
T
S
M
P
D
G
S
V
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P51567
427
49548
S351
L
K
K
V
D
R
H
S
E
K
Y
V
R
R
G
Baker's Yeast
Sacchar. cerevisiae
P32350
737
83824
K577
D
K
M
F
Y
K
S
K
H
K
L
G
N
S
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
51.2
91.5
N.A.
96.7
59.9
N.A.
N.A.
21.2
N.A.
74.9
N.A.
37
N.A.
20.4
N.A.
Protein Similarity:
100
99.8
62.3
91.7
N.A.
98.1
73.7
N.A.
N.A.
39.7
N.A.
83.8
N.A.
48.4
N.A.
34.5
N.A.
P-Site Identity:
100
100
66.6
100
N.A.
100
66.6
N.A.
N.A.
6.6
N.A.
100
N.A.
53.3
N.A.
6.6
N.A.
P-Site Similarity:
100
100
80
100
N.A.
100
80
N.A.
N.A.
20
N.A.
100
N.A.
60
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
39
24.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
56.9
43.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
9
0
0
0
0
0
17
0
0
0
50
% D
% Glu:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% E
% Phe:
0
0
0
9
0
0
0
0
67
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
92
17
0
9
% G
% His:
17
0
0
0
0
0
9
0
9
0
9
0
0
0
0
% H
% Ile:
0
0
0
0
0
9
0
0
0
0
0
0
0
9
9
% I
% Lys:
0
59
17
0
67
9
67
9
0
17
17
0
9
0
0
% K
% Leu:
9
0
0
0
0
0
0
0
9
0
9
0
0
67
0
% L
% Met:
0
0
9
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% N
% Pro:
17
0
0
0
0
0
0
0
0
9
0
0
0
0
9
% P
% Gln:
0
0
0
0
0
59
0
0
0
0
0
0
0
0
0
% Q
% Arg:
42
34
0
59
0
9
0
0
0
0
42
0
50
9
0
% R
% Ser:
0
9
0
0
0
0
9
17
0
9
0
0
17
9
0
% S
% Thr:
0
0
59
9
17
9
17
9
0
0
0
0
0
0
0
% T
% Val:
0
0
0
9
0
0
0
0
0
0
0
9
0
9
25
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
17
0
9
0
0
67
0
67
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _